Recent research studying almost 44,000 men and women finds that higher levels of vitamin C in vitamin E in the diet are associated with lower risk of Parkinson’s Disease1.
vitamini C and E are antioxidants2. Antioksidanti preprečujejo oksidativni stres, ki ga povzročajo zelo reaktivne molekule, znane kot prosti radikali2. Oksidativni stres ima različne vire, kot so sončna svetloba, onesnaženost zraka, cigaretni dim in vadba2. Oksidativni stres lahko povzroči poškodbe celic (s poškodbami molekul v telesu) in lahko prispeva k številnim boleznim, kot so rak, bolezni srca, sladkorna bolezen, Alzheimerjeva bolezen, Parkinsonova bolezen in celo očesne bolezni.2. Zato so antioksidanti lahko koristni za preprečevanje molekularnih poškodb in ohranjanje zdravja celic.
A recent Swedish study explored the effects of certain dietary factors on the incidence of development of Parkinsonova bolezen (PD) in almost 44,000 men and women1. These factors included dietary intake of vitamin C, vitamin E and beta-carotene1. Vnos teh specifičnih mikrohranil so primerjali z incidenco PD v skupini1.
Beta-karoten ni imel povezave s tveganjem za PD1. However, intake of vitamini C and E was inversely correlated to the risk of PD1 kar kaže, da so ti antioksidanti zagotovili določen nevroprotektivni učinek, ki je zmanjšal pojavnost PD.
This study may allow the inference that it may be beneficial to increase these vitamini in the diet to reduce risk of PD, but it does not necessarily mean that the association seen was caused by the intake of these vitamini, as people ingesting more of these vitamini might just have healthier diets and lifestyles. It may be the case that there was a causal relationship but this is hard to prove from an association study. There could also be a non-causal relationship; supporting this is the finding from an older study comparing levels of antioxidants in the blood of PD patients which found no evidence that antioxidants contributed to onset or progression of PD3. Lastly, both theories may be true, where vitamini C and E in diet played a minor role. Regardless, the overall message of intaking enough vitamin C (such as through eating oranges and strawberries) and vitamin E (such as through eating nuts and seeds) is probably conducive to good health.
***
Reference:
- Hantikainen E., Lagerros Y., et al 2021. Prehranski antioksidanti in tveganje za Parkinsonovo bolezen. Švedska nacionalna marčevska kohorta. Nevrologija, februar 2021, 96 (6) e895-e903; DOI: https://doi.org/10.1212/WNL.0000000000011373
- NIH 2021. Antioksidanti: v globino. Na voljo na spletu na https://www.nccih.nih.gov/health/antioxidants-in-depth
- King D., Playfer J. in Roberts N., 1992. Koncentracije vitaminov A, C in E pri starejših bolnikih s Parkinsonovo boleznijo.Postgrad Med J(1992)68,634-637. Na voljo na spletu na https://pmj.bmj.com/content/postgradmedj/68/802/634.full.pdf
***
